Oxidative damage of the extracts of condensate, particulate and semivolatile organic compounds from gasoline engine exhausts on testicles of rats.
نویسندگان
چکیده
Oxidative damage induced by extracts of condensate, particulate matters and semivolatile organic compounds from gasoline engine exhausts were investigated in testicles of adult Sprague-Dawley rats. The results showed that gasoline engine exhaust could increase the contents of malondialdehyde and carbonyl protein, decrease activities of superoxide dismutase and glutathione peroxidase, and induce DNA damage in testicle of rat. Taking together, the gasoline engine exhaust could promote oxidative damage of bio-macromolecular in testicles of rat and oxidative stress might be an alternative mechanism for male reproductive function of male mammals.
منابع مشابه
Dioxin-receptor ligands in urban air and vehicle exhaust.
The ability of extracts of urban air and vehicle exhaust particulates to bind to the dioxin receptor has been determined. It was shown that such extracts do contain significant amounts of dioxin-receptor binding activity. The level of dioxin-receptor binding found in ambient air reflects its pollution level as determined by mutagenic activity. Furthermore, it was shown that the extracts of both...
متن کاملGas/Particle Partitioning of Semivolatile Organic Compounds To Model Inorganic, Organic, and Ambient Smog AerosolsGas/Particle Partitioning of Semivolatile Organic Compounds To Model Inorganic, Organic, and Ambient Smog Aerosols
Gas/particle (G/P) partitioning is an important process that affects the deposition, chemical reactions, long-range transport, and impact on human and ecosystem health of atmospheric semivolatile organic compounds (SOCs). Gas/ particle partitioning coefficients (Kp) were measured in an outdoor chamber for a group of polynuclear aromatic hydrocarbons (PAHs) and n-alkanes sorbing to three types o...
متن کاملComparison of immunotoxic effects induced by the extracts from methanol and gasoline engine exhausts in vitro.
Gasoline engine exhaust has been considered as a major source of air pollution in China. Due to lower cyto- and geno-toxicity effects of methanol engine exhaust, methanol is regarded as a potential substitute for gasoline. We have previously compared cyto- and geno-toxicities of gasoline engine exhaust with that of methanol engine exhaust in A549 cells (Zhang et al., 2007).To characterize the i...
متن کاملDNA binding of polycyclic aromatic hydrocarbons in a human bronchial epithelial cell line treated with diesel and gasoline particulate extracts and benzo[a]pyrene.
Particulate matter of vehicle exhaust is known to contain carcinogenic compounds such as polycyclic aromatic hydrocarbons (PAH) and is suggested to increase lung cancer risk in humans. This study examines the differences in diesel and gasoline-derived PAH binding to DNA in a human bronchial epithelial cell line (BEAS-2B). Particulate matter (PM) of gasoline exhaust was collected from passenger ...
متن کاملData from short-term tests on motor vehicle exhausts
The mutagenicity of motor vehicle exhausts has been studied by using Salmonella typhimurium strains TA 98 and TA 100. Acetone extracts of the particulate phase and the gas phase have been tested in the presence and absence of a metabolizing system (S9). The particulate phases from medium- and heavy-duty diesel vehicles were tested. The vehicles were driven according to a modified 13 mode test, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Bulletin of environmental contamination and toxicology
دوره 83 1 شماره
صفحات -
تاریخ انتشار 2009